abstract：PURPOSE OF REVIEW:To summarize clinical evidence for intraoperative ventilation settings, which could protect against postoperative pulmonary complications (PPCs) in surgical patients with uninjured lungs. RECENT FINDINGS:There is convincing evidence for protection against PPCs by low tidal volumes: benefit was found ...

journal_title：Current opinion in critical care

authors： Schultz MJ,Abreu MG,Pelosi P

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the progress made over the past 20 years in the treatment of septic shock, mortality remains high. Microcirculatory disorders raise considerable interest aiming to improve the understanding of the physiopathology of septic shock and its management. RECENT FINDINGS:Numerous experimental and cl...

journal_title：Current opinion in critical care

authors： Ait-Oufella H,Bourcier S,Lehoux S,Guidet B

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will provide an overview of actual data concerning perioperative risk. Furthermore, strategies to prevent, detect and treat perioperative complications will be discussed. RECENT FINDINGS:Perioperative in-hospital mortality rate of 0.4-4% has not improved over the last years possibly resul...

journal_title：Current opinion in critical care

authors： Boehm O,Baumgarten G,Hoeft A

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review the recent literature describing how to assess and treat postcardiac arrest syndrome associated haemodynamics and manage oxygenation and ventilation derangements. RECENT FINDINGS:Postcardiac arrest syndrome is a well described entity that includes systemic ische...

journal_title：Current opinion in critical care

authors： Topjian AA,Berg RA,Taccone FS

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a summary of the recent literature on extracorporeal membrane oxygenation (ECMO) in adults with severe acute respiratory distress syndrome (ARDS), focusing on advances in equipment, current conventional and unconventional indications, complications, and future applications. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Leligdowicz A,Fan E

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to critically ill patients has resulted in a recent shift in ARDS research. Increasin...

journal_title：Current opinion in critical care

authors： Festic E,Kor DJ,Gajic O

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is a frequent and serious event associated with a high rate of complications, with an increased risk of progression to multiple organ dysfunction and excessive 'attributable' mortality. AKI affects all physiologic functions and organ systems with interrelated mechanisms, incl...

journal_title：Current opinion in critical care

authors： Druml W

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Securing the airway to provide sufficient oxygenation and ventilation is of paramount importance in the management of all types of emergency patients. Particularly in severely injured patients, strategies should be adapted according to useful recent literature findings. RECENT FINDINGS:The role of ou...

journal_title：Current opinion in critical care

authors： Beckers SK,Brokmann JC,Rossaint R

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although providing palliative care in the ICU has become a priority, the success of different methods to integrate palliative care into the ICU has varied. This review examines the current evidence supporting the different models of palliative care delivery and highlights areas for future study. RECE...

journal_title：Current opinion in critical care

authors： Hua M,Wunsch H

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is commonplace in most ICUs. In many cases the cause is believed to be multifactorial with sepsis being a major component. However, occasionally intrinsic renal disease will present to the ICU and as such critical care practitioners should be aware of this possibility and the...

journal_title：Current opinion in critical care

authors： Amery CE,Forni LG

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Fluid removal and relief of congestion are central to treatment of acute heart failure. Diuretics have been the decongestive mainstay but their known limitations have led to the exploration of alternative strategies. This review compares diuretics with ultrafiltration and examines the recent evidence ...

journal_title：Current opinion in critical care

authors： Krishnamoorthy A,Felker GM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutic hypothermia following out-of-hospital cardiac arrest improves neurological recovery. Coupled with neurological benefit, multiple complications including infection have been associated with therapeutic hypothermia following out-of-hospital cardiac arrest. In this review, we will discuss the...

journal_title：Current opinion in critical care

authors： Kuchena A,Merkel MJ,Hutchens MP

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There are few first-hand accounts that describe the history of outcome prediction in critical care. This review summarizes the authors' personal perspectives about the development and evolution of Acute Physiology and Chronic Health Evaluation over the past 35 years. RECENT FINDINGS:We emphasize what...

journal_title：Current opinion in critical care

authors： Zimmerman JE,Kramer AA

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS:The cost of over-aggressive fluid resuscitation is increased organ failure and mortality. In anticipation of the upcom...

journal_title：Current opinion in critical care

authors： Douglas JJ,Walley KR

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite decades of advances in prehospital and in-hospital medical care, patients with out-of-hospital cardiac arrest continue to have poor neurologic and cardiac function following otherwise successful resuscitation. This review examines the mechanisms and therapeutic strategies currently under devel...

journal_title：Current opinion in critical care

authors： Bartos JA,Debaty G,Matsuura T,Yannopoulos D

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute liver failure (ALF) is associated with significant mortality. Although specific therapies may be available, the evidence base for these and for many aspects of supportive therapy has been slow to emerge. Liver transplantation continues to be a cornerstone of treatment, and the management of ALF,...

journal_title：Current opinion in critical care

authors： Willars C

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Fever is common in the ICU among patients with severe brain injury. Fever has been consistently shown to exacerbate brain injuries in animal models and has been consistently associated with poor outcome in human studies. However, whether fever control improves outcome and the ideal means of fever cont...

journal_title：Current opinion in critical care

authors： Bohman LE,Levine JM

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To explore the origin of myths and their progression toward dogma. The process of debunking myths in the neurocritical care unit (NCCU) is facilitated if nurses are involved early during the process. RECENT FINDINGS:Current and past practices in the NCCU were reviewed through our personal experiences...

journal_title：Current opinion in critical care

authors： Olson DM,Figueroa SA

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome (ARDS) is a multifaceted lung disease with no current effective therapy. Many clinical trials using conventional pharmacologic therapies have failed, suggesting the need to examine alternative approaches. Thus, attention has focused on the therapeutic potential of c...

journal_title：Current opinion in critical care

authors： Maron-Gutierrez T,Laffey JG,Pelosi P,Rocco PR

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is a frequent finding in critically ill patients and is associated with adverse outcomes. With the purpose of improving outcome of AKI, the Kidney Disease: Improving Global Outcomes (KDIGO) group, a group of experts in critical care nephrology, has presented a set of guidelin...

journal_title：Current opinion in critical care

authors： Hoste EA,De Corte W

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Increased use of advanced life-sustaining measures in patients with poor long-term expectations secondary to more chronic organ dysfunctions, comorbidities and/or a poor quality of life has become a worrying trend over the last decade. This can lead to futile, disproportionate or inappropriate care in...

journal_title：Current opinion in critical care

authors： Kompanje EJ,Piers RD,Benoit DD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Uncertainty surrounding medical decision-making is particularly important during end-of-life decision-making. Doubts about the patient's best interests and prognostic accuracy may lead to conflict. RECENT FINDINGS:Many authors have suggested recently that medical attitudes to uncertainty need review....

journal_title：Current opinion in critical care

authors： Ridley S,Fisher M

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Professional organizations, consensus groups, and stakeholders are calling for better palliative care in acute care settings, particularly in ICUs. Our ability to deliver that care is dependent on the outcomes associated with palliative care in the ICU. This review provides a conceptual framework for ...

journal_title：Current opinion in critical care

authors： Aslakson RA,Bridges JF

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The ultimate goal of cardiopulmonary resuscitation is long-term neurologically intact survival. Despite numerous well-designed studies, the medications currently used in advanced cardiac life support have not demonstrated success in this regard. This review describes the novel therapeutics under inves...

journal_title：Current opinion in critical care

authors： Bartos JA,Yannopoulos D

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. RECENT FINDINGS:Hydraulic conductivity is kept...

journal_title：Current opinion in critical care

authors： Jacob M,Chappell D

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:There is significant controversy for perioperative fluid management. This review discusses the evidence from clinical studies, basic research, and systematic reviews to provide a summary of the current best practice in this area. RECENT FINDINGS:Recent evidence has challenged the long-held contention...

journal_title：Current opinion in critical care

authors： Peng ZY,Kellum JA

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of the invasive monitoring techniques pulmonary artery catheter (PAC) and transpulmonary thermodilution (TPD) for cardiopulmonary monitoring in the critically ill patient. RECENT FINDINGS:Characterization of the nature of hemodynamic alterations and hemodynamic optimization can be...

journal_title：Current opinion in critical care

authors： De Backer D,Fagnoul D,Herpain A

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the current literature dealing with pathophysiology, diagnostics, bleeding management, and thromboprophylaxis in patients with acute and chronic liver dysfunction. RECENT FINDINGS:Routine coagulation tests such as prothrombin time and International Normalized Ratio (INR) are not ...

journal_title：Current opinion in critical care

authors： Schaden E,Saner FH,Goerlinger K

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Early prognostication in acute brain damage remains a challenge in the realm of critical care. There remains controversy over the most optimal methods that can be utilized to predict outcome. The utility of recently reported prognostic biomarkers and clinical methods will be reviewed. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Kalanuria AA,Geocadin RG

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:End-of-life care and communication deficits are important sources of conflicts within ICU teams and with patients or families. This narrative review describes recent studies on how to improve palliative care and surrogate decision-making in ICUs and compares the results with previously published liter...

journal_title：Current opinion in critical care

authors： Wiedermann CJ,Lehner GF,Joannidis M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Survival of critically ill patients is frequently associated with significant functional impairment and reduced health-related quality of life. Early rehabilitation of ICU patients has recently been identified as an important focus for interdisciplinary ICU teams. However, the amount of rehabilitation...

journal_title：Current opinion in critical care

authors： Gosselink R,Needham D,Hermans G

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantable cardioverter-defibrillator (ICD) implantation is the standard of care for secondary prevention in patients with previous cardiac arrest and for primary prevention in appropriately selected patients with cardiomyopathy. However, ICD therapies and the arrhythmias that trigger these therapies...

journal_title：Current opinion in critical care

authors： Bradfield JS,Buch E,Shivkumar K

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the results of case series and trials which evaluated venovenous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. Potential indications of the technique in this setting are discussed. RECENT FINDINGS:Major technological improvements in extracorporeal ...

journal_title：Current opinion in critical care

authors： Combes A,Bréchot N,Luyt CE,Schmidt M

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize important publications in enhanced recovery during 2010-2011 and to highlight key themes. Specifically, we focus on updated systematic reviews of high-quality clinical trials of enhanced recovery in colorectal surgery, exemplar studies of enhanced recovery in oth...

journal_title：Current opinion in critical care

authors： Grocott MP,Martin DS,Mythen MG

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Delirium is frequently encountered in the ICU and is associated with significant adverse outcomes. The increasingly recognized consequences of ICU delirium should enhance efforts to improve recognition and management of this serious problem. We aim to review the recent literature on ICU delirium, incl...

journal_title：Current opinion in critical care

authors： Jones SF,Pisani MA

更新日期：2012-04-01 00:00:00

abstract：PURPOSE OF REVIEW:As incidence of acute lung injury (ALI) increases and case fatality decreases, long-term care of survivors is of public health importance. Previous studies demonstrate that these survivors are at risk for impairment in physical, cognitive and mental health. In this review, we will discuss recent studi...

journal_title：Current opinion in critical care

authors： Hough CL,Herridge MS

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Traumatic injury continues to be a significant cause of morbidity and mortality in the year 2011. In addition, the healthcare expenditures and lost years of productivity represent significant economic cost to the affected individuals and their communities. Helicopters have been used to transport traum...

journal_title：Current opinion in critical care

authors： Plevin RE,Evans HL

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The scope of this review is to describe what is known about injury outcomes and the principles by which they can be improved by acute phase interventions. Assessing which outcomes matter to trauma patients is important both for the evaluation of existing and novel acute interventions and to assess the...

journal_title：Current opinion in critical care

authors： Brohi K,Cole E,Hoffman K

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Health-related quality of life (HRQoL) is an important patient-reported outcome measure following critical illness. 'Validated' and professionally endorsed generic measures are widely used to evaluate critical care intervention and guide practice, policy and research. Although recognizing that they ar...

journal_title：Current opinion in critical care

authors： Ramsay P

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Postoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Fried E,Weissman C,Sprung C

更新日期：2011-08-01 00:00:00